人参总皂苷抑制甲基苯丙胺诱导的多巴胺能神经元耗竭。
Ginseng total saponin inhibits the dopaminergic depletions induced by methamphetamine.
作者信息
Oh K W, Kim H S, Wagner G C
机构信息
Department of Pharmacology, College of Pharmacy, Chungbuk National University, Cheongju, Korea.
出版信息
Planta Med. 1997 Feb;63(1):80-1. doi: 10.1055/s-2006-957610.
PMID:9063099
Abstract
Pretreatment with ginseng total saponin (GTS) reduced the magnitude of the methamphetamine-induced dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC), and homovanillinic acid (HVA) depletions. It is suggested that GTS can, in part, prevent the methamphetamine-induced striatal dopaminergic depletions.
摘要
人参总皂苷（GTS）预处理可减轻甲基苯丙胺诱导的多巴胺（DA）、3,4-二羟基苯乙酸（DOPAC）和高香草酸（HVA）耗竭的程度。提示GTS可部分预防甲基苯丙胺诱导的纹状体多巴胺能神经元耗竭。
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