Andrade-Mena C E
Department of Scientific Investigation, University Centre of Health Sciences, University of Guadalajara, México.
Int J Tissue React. 1996;18(2-3):81-5.
The values observed in this series of experiments showed that CD 8+ spleen T cells obtained from 15-mg/kg carbamazepine (CBZ)-treated donor mice were capable of diminishing both humoral and cellular immune responses of normal spleen cells when transferred into lethally irradiated recipient animals. Immune responses were evaluated by enumeration of direct and indirect plaque-forming spleen cells (PFC) and by the delayed-type hypersensitivity reaction (DTH) to sheep red blood cells.
在这一系列实验中观察到的值表明，从接受15毫克/千克卡马西平（CBZ）治疗的供体小鼠获得的CD8 +脾T细胞，当转移到经致死性照射的受体动物体内时，能够减弱正常脾细胞的体液免疫和细胞免疫反应。通过计数直接和间接斑块形成脾细胞（PFC）以及对绵羊红细胞的迟发型超敏反应（DTH）来评估免疫反应。
