Wolf J P, Bulwa S, Feneux D, De Almeida M, Kerdrain C, Amer M, Diaz I, Khen N, Rodrigues D, Jouannet P
Laboratoire d'Histologie-Embryologie à orientation en Biologie de la Reproduction, Hôpital Cochin, Paris.
Contracept Fertil Sex. 1997 Jan;25(1):69-78.
Subzonal insemination was the first micromanipulation technique used in the treatment of male factor sterility. Analysis of the sperm pathology prior to patient inclusion in the program allowed us to study gamete interaction in the human and the early embryogenesis. A series of 523 cycles and 3,027 micro-injected oocytes is reported.
卵周隙内授精是用于治疗男性因素不育症的首个显微操作技术。在患者纳入该项目之前对精子病理学进行分析,使我们能够研究人类配子间的相互作用以及早期胚胎发育过程。本文报告了一系列共523个周期以及3027个经显微注射的卵母细胞。