Honig A, Lousberg R, Wojciechowski F L, Cheriex E C, Wellens H J, van Praag H M
Academisch Ziekenhuis, Maastricht, Afd. Psychiatrie.
Ned Tijdschr Geneeskd. 1997 Jan 25;141(4):196-9.
To determine frequency and clinical features of major depressive disorder according to DSM IV criteria in patients following a first myocardial infarction.
Questionnaire.
Departments of Cardiology and Psychiatry, University Hospital Maastricht, the Netherlands.
Depression was assessed using the Zung 'Self-rating depression scale' (Zung-SDS) and the 'Symptom checklist' (SCL)-90 in 228 patients who filled the questionnaires out themselves (response: 60-70%), 1, 3, 6 en 12 months after their first heart attack. When the score on one or both lists was above threshold, the patient was invited for a clinical interview with a psychiatrist.
One month post infarction 10% were diagnosed with a major depressive episode, a percentage which increased to 34% one year post infarction. The clinical features of the depression in these patients were the same as in a matched sample of depressed psychiatric inpatients without a cardiac history, except that hostility was significantly increased in the post-infarction patients. There was no mortality.
Depressive disorder is a frequent comorbid disease after a first myocardial infarction.
根据《精神疾病诊断与统计手册》第四版标准，确定首次心肌梗死后患者中重度抑郁症的发病率及临床特征。
问卷调查。
荷兰马斯特里赫特大学医院心脏病科和精神科。
对228名在首次心脏病发作后1、3、6和12个月自行填写问卷的患者（回复率为60 - 70%），使用zung氏自评抑郁量表（Zung-SDS）和症状自评量表（SCL）-90评估抑郁情况。当一个或两个量表的得分高于临界值时，邀请患者接受精神科医生的临床访谈。
梗死1个月后，10%的患者被诊断为重度抑郁发作，这一比例在梗死后1年增至34%。这些患者抑郁症的临床特征与无心脏病史的匹配抑郁精神科住院患者样本相同，但梗死患者的敌意明显增加。无死亡病例。
抑郁症是首次心肌梗死后常见的共病。
