Walter E
Medizinische Universitätsklinik Freiburg.
Praxis (Bern 1994). 1997 Jan 21;86(4):102-3.
A specific medical therapy for 'the hepatorenal syndrome' (HRS) is not available. However, the increasing knowledge of the mechanisms involved in the development of HRS leads to new therapeutic approaches to this syndrome of functional renal failure. Recognition and prevention of precipitating factors, the correction and treatment of prerenal failure and acute tubular necrosis are particularly important in the treatment of patients with liver cirrhosis, ascites and hepato-renal failure. Vasoconstrictor agents (ornipressin, dopamine) are administered to achieve an improvement of the systemic circulation. Definitive therapy of HRS is liver transplantation.
目前尚无针对“肝肾综合征”(HRS)的特效药物治疗方法。然而,随着对肝肾综合征发病机制的深入了解,出现了针对这种功能性肾衰竭综合征的新治疗方法。识别并预防诱发因素,纠正和治疗肾前性肾衰竭及急性肾小管坏死,对于肝硬化、腹水和肝肾衰竭患者的治疗尤为重要。可使用血管收缩剂(鸟氨加压素、多巴胺)来改善体循环。肝肾综合征的最终治疗方法是肝移植。