Dzembak T M, Gurkalo V K, Gershanovich M L
Vopr Onkol. 1996;42(5):63-6.
Non-Hodgkin's malignant lymphoma was diagnosed in 66 patients by immunophenotype technique using a batch of 13 Russian-isolated monoclonal antibodies which help identify antigens of T- and B-lymphocyte surface membranes. Polyclonal light chains of immunoglobulins and T- and B-cell antigens were identified in the course of histological examination of biopsy material sampled from hyperplasia lymphoid tissue. B-cell lymphomas revealed monoclonal light chains of immunoglobulins and positive B-cell antigens. T-cell tumors had mostly T-cell antigens and no light chains of immunoglobulins. Neither common leukocyte antigen, nor panT- or panB-cell antigens were found in 7 cases of cancer metastasis to lymph nodes.
采用一批13种俄罗斯产单克隆抗体的免疫表型技术，对66例患者诊断为非霍奇金恶性淋巴瘤，这些抗体有助于识别T和B淋巴细胞表面膜抗原。在对取自增生性淋巴组织的活检材料进行组织学检查过程中，鉴定出免疫球蛋白的多克隆轻链以及T和B细胞抗原。B细胞淋巴瘤显示免疫球蛋白的单克隆轻链和阳性B细胞抗原。T细胞肿瘤大多有T细胞抗原，无免疫球蛋白轻链。7例癌症转移至淋巴结的病例中，未发现共同白细胞抗原、泛T或泛B细胞抗原。
