Leblanc C, Richard O, Kloareg B, Viehmann S, Zetsche K, Boyen C
Station Biologique de Roscoff, C.N.R.S.-UPR 9042, Université Pierre et Marie Curie, BP 74, F-29682 Roscoff cedex, France.
Curr Genet. 1997 Mar;31(3):193-207. doi: 10.1007/s002940050196.
The purpose of this review is to present an account of our current understanding of the structure, organization and evolution of mitochondrial genomes, and to discuss the origin and evolution of mitochondria from the perspective recently provided by the extensive sequencing of various mitochondrial genomes. Mitochondrial-en-coded protein phylogenies are congruent with nuclear phylogenies and strongly support a monophyletic origin of mitochondria. The newly available data from red-algal mitochondrial genomes, in particular, show that the structural and functional diversity of mitochondrial genomes can be accounted for by paralogous evolution. We also discuss the influence of other constraints, such as uniparental inheritance, on the evolution of genome organization in mitochondria.
本综述的目的是阐述我们目前对线粒体基因组的结构、组织和进化的理解，并从最近各种线粒体基因组的广泛测序所提供的角度讨论线粒体的起源和进化。线粒体编码的蛋白质系统发育与核系统发育一致，并有力地支持了线粒体的单系起源。特别是来自红藻线粒体基因组的新数据表明，线粒体基因组的结构和功能多样性可以通过旁系同源进化来解释。我们还讨论了其他限制因素，如单亲遗传，对线粒体基因组组织进化的影响。
