Grayson W, Leiman G, Cooper K
School of Pathology, University of the Witwatersrand, South African Institute for Medical Research, Johannesburg.
Gen Diagn Pathol. 1997 Feb;142(3-4):247-52.
We report the cytologic and histopathologic features of an unusual peripheral primary lung tumor in a 61-year-old female. The central portion showed features of typical pulmonary chondroid hamartoma (mesenchymoma). Arising from the peripheral margin of this tumor, however, was an exuberant proliferation of papillary mesenchymal structures lined by type 2 pneumocates, mimicking papillary sclerosing hemangioma (pneumocytoma). This extreme example of fibroadenomatoid proliferation shares histologic features with other pulmonary neoplasms characterized by mesenchymal cores lined by type 2 pneumocytes. We propose that such lesions be unified under the term "alveolar mixed tumor".
我们报告了一名61岁女性患者中一种不寻常的外周原发性肺肿瘤的细胞学和组织病理学特征。肿瘤中央部分呈现典型肺软骨样错构瘤(间叶瘤)的特征。然而,从该肿瘤的外周边缘长出了由II型肺泡上皮细胞衬覆的乳头样间叶结构的旺盛增殖,类似乳头硬化性血管瘤(肺细胞瘤)。这种纤维腺瘤样增殖的极端例子与其他以II型肺泡上皮细胞衬覆的间叶核心为特征的肺肿瘤具有共同的组织学特征。我们建议将此类病变统一命名为“肺泡混合瘤”。