Repetto L, Costantini M, Campora E, Amoroso D, Gianni W, Catturich A, Vecchio C, Simoni C, Marigliano V, Rosso R, Santi L
Department of Medical Oncology I, University La Sapienza, Rome, Italy.
Breast Cancer Res Treat. 1997 Mar;43(1):27-31. doi: 10.1023/a:1005784208787.
The medical records of all women (297 cases) with breast cancer > or = 70 years of age, presenting at our Institute from January 1980 to December 1989, were reviewed. Data from 226 elderly women was compared to that from 100 stage-matched patients < 50 years of age, presenting during the same 10-year study interval. Conservative surgery was significantly more frequent in young patients (71.1%) compared to elderly women (26.1%) and radical mastectomy according to Halsted was undertaken in 34.3% of the elderly group compared to 8.9% of young patients (p < 0.001). Since 'incidental' diagnosis was significantly more frequent in the elderly group (59.9% versus 6.0%) (p < 0.001), primary care physicians may play an important role in the early diagnosis of breast cancer in the majority of elderly women.
回顾了1980年1月至1989年12月期间在我院就诊的所有年龄≥70岁的乳腺癌女性患者（297例）的病历。将226例老年女性的数据与100例年龄<50岁、在相同10年研究期间就诊且分期匹配的患者的数据进行了比较。与老年女性（26.1%）相比，保乳手术在年轻患者中更为常见（71.1%）；按照Halsted术式进行的根治性乳房切除术在老年组中的比例为34.3%，而在年轻患者中为8.9%（p<0.001）。由于老年组“偶然”诊断更为常见（59.9%对6.0%）（p<0.001），初级保健医生在大多数老年女性乳腺癌的早期诊断中可能发挥重要作用。
