糖尿病性硬化性水肿：一例报告及糖胺聚糖的生化分析

Diabetic scleredema: a case report and biochemical analysis for glycosaminoglycans.

作者信息

Kobayashi T, Yamasaki Y, Watanabe T

机构信息

Division of Dermatology, Tokyo Daini National Hospital, Higashigaoka, Meguro, Japan.

出版信息

J Dermatol. 1997 Feb;24(2):100-3. doi: 10.1111/j.1346-8138.1997.tb02751.x.

DOI:10.1111/j.1346-8138.1997.tb02751.x

PMID:9065704

Abstract

We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid.

摘要

我们报告一例患有典型糖尿病性硬化症病变的患者。受累皮肤的组织学检查结果显示真皮增厚、粘蛋白沉积和纤维化。生化分析表明，受累皮肤以及皮肤狼疮粘蛋白病中的糖胺聚糖均增加。粘液性物质由透明质酸组成。