Kobayashi T, Yamasaki Y, Watanabe T
Division of Dermatology, Tokyo Daini National Hospital, Higashigaoka, Meguro, Japan.
J Dermatol. 1997 Feb;24(2):100-3. doi: 10.1111/j.1346-8138.1997.tb02751.x.
We report a patient with the typical lesions of diabetic scleredema. Histological findings of the involved skin were thickening of the dermis, depositions of mucins, and fibrosis. Biochemical analysis revealed an increase in glycosaminoglycans in the involved skin as well as in the cutaneous lupus mucinosis. Mucinous materials were composed of hyaluronic acid.