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胰腺切除术:其对骨骼和钙代谢的影响(作者译)

[Resections of the pancreas: their effects on bone and calcium metabolism (author's transl)].

作者信息

Dammann H G, Kruse H P, Kuhlencordt F, Montz R, Schreiber H W

出版信息

Z Gastroenterol. 1977 Sep;15(9):577-85.

PMID:906605
Abstract

Four to ten years after partial or total resections of the pancreas calcium and bone metabolism was investigated. A high-turnover osteoporosis is proved by bone histomorphometry. There were no signs of osteomalacia or secondary hyperparathyroidism. Radiocalciumkinetics in all cases showed an increase endogenous fecal loss of calcium. Both, intestinal absorption and renal excretion of calcium were normal. Pathophysiologic relationship between resections of the pancreas and their influence on calcium and bone metabolism has not been sufficiently explained until now. Further investigation will be necessary.

摘要

在胰腺部分或全部切除术后4至10年,对钙和骨代谢进行了研究。骨组织形态计量学证实存在高转换型骨质疏松症。没有骨软化症或继发性甲状旁腺功能亢进的迹象。所有病例的放射性钙动力学均显示内源性粪便钙流失增加。钙的肠道吸收和肾脏排泄均正常。迄今为止,胰腺切除术与其对钙和骨代谢的影响之间的病理生理关系尚未得到充分解释。有必要进行进一步研究。

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