Pulido-Méndez M, Finol H J, Márquez A, Aguilar I, Girón M E, González N, Rodríguez-Acosta A
Institute of Experimental Medicine, Central University of Venezuela, Caracas, Venezuela.
J Submicrosc Cytol Pathol. 1997 Jan;29(1):99-104.
The ultrastructural study of adrenal cortex from Plasmodium berghei infected mice showed different degrees of capillary wall alterations including disruption and widening of the fenestrae, capillaries packed with parasitized erythrocytes, necrosis of cortical cells, parasitized erythrocytes outside capillaries and in some instances inside cortical cell cytoplasm. Lymphocytes were also observed in degenerated cortical cells. Our results suggest that adrenal cortex lesions may be relevant in the etiopathogenesis of severe malaria.
对感染伯氏疟原虫小鼠的肾上腺皮质进行超微结构研究发现，毛细血管壁存在不同程度的改变，包括窗孔破裂和增宽、充满被寄生红细胞的毛细血管、皮质细胞坏死、毛细血管外甚至某些情况下皮质细胞质内的被寄生红细胞。在退化的皮质细胞中也观察到淋巴细胞。我们的结果表明，肾上腺皮质病变可能与重症疟疾的发病机制有关。
