Rajagopalan R, Anderson R T
Glaxo Wellcome Inc, Research Triangle Park, NC 27709, USA.
Am J Contact Dermat. 1997 Mar;8(1):26-31.
According to the National Center for Health Statistics Survey, a large proportion of patients with contact dermatitis, atopic dermatitis, or eczema visit nondermatologists, and only approximately 40% visit dermatologists. Therefore, the prompt, proper diagnosis of the cause and prescription of precise treatment can be delayed. We wanted to create a clear understanding of the nuances of the allergic contact dermatitis and its effect on the economics and life quality of the patients for not only the dermatologists but also the primary care physicians. In an observational multicenter study planned for a span of 1 year with approximately 570 patients suspected of allergic contact dermatitis, data were collected at enrollment on their history, physical characteristics, and quality of life and were analyzed using routine statistical procedures. The "quality of life" data on these patients, most of whom have a history of long-standing disease, show a high correlation between the clinical factors such as symptom activity and frequency of episodes and the subscales of quality of life. These patients had a lesser score on mental and vital subscales (SF-36) than US population norms, showing a moderate impact of the disease on their mental health and vitality. There is an urgent need for a simpler and quicker method that could lead to an earlier and more precise diagnosis so the causal substance can be identified and avoided and the disease treated in a timely and cost-effective manner.
根据美国国家卫生统计中心的调查,很大一部分接触性皮炎、特应性皮炎或湿疹患者会去看非皮肤科医生,只有约40%的患者会去看皮肤科医生。因此,病因的及时、正确诊断以及精确治疗的处方可能会被延迟。我们希望不仅让皮肤科医生,也让初级保健医生清楚了解过敏性接触性皮炎的细微差别及其对患者经济状况和生活质量的影响。在一项为期1年的观察性多中心研究中,对约570名疑似过敏性接触性皮炎的患者进行了研究,在入组时收集了他们的病史、身体特征和生活质量数据,并使用常规统计程序进行分析。这些患者大多有长期疾病史,其“生活质量”数据显示,症状活动和发作频率等临床因素与生活质量子量表之间存在高度相关性。这些患者在精神和活力子量表(SF-36)上的得分低于美国人群标准,表明该疾病对他们的心理健康和活力有中度影响。迫切需要一种更简单、更快捷的方法,以便能更早、更精确地做出诊断,从而识别并避免致病物质,并及时且经济高效地治疗该疾病。