Zubenko G S, Marino L J, Sweet R A, Rifai A H, Mulsant B H, Pasternak R E
Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA.
Biol Psychiatry. 1997 Mar 15;41(6):724-36. doi: 10.1016/S0006-3223(96)00337-X.
A multidisciplinary diagnostic evaluation was performed for 868 older psychiatric inpatients during a 46-month interval. A total of 402 (46%) met DSM-III-R criteria for organic mental disorders, 329 (38%) had mood disorders, 90 (10%) had psychotic disorders, and 47 (5%) had other mental disorders or conditions. Concurrent medical problems were systematically assessed and classified according to ICD-9-CM criteria. The patients suffered from a mean of 5.6 +/- 3.1 (SD) active medical problems (range 0-18). This level of medical comorbidity was significantly greater than that of older psychiatric outpatients and comparable to that of elderly inpatients in general medical hospitals. When the effects of age and education were controlled for, there were no significant differences in mean numbers of medical problems among the four groups of psychiatric inpatients. An association of major depression with diseases of the digestive system was observed and may be related to peripheral autonomic dysregulation.
在46个月的时间里，对868名老年精神科住院患者进行了多学科诊断评估。共有402名（46%）符合DSM-III-R器质性精神障碍标准，329名（38%）患有情绪障碍，90名（10%）患有精神障碍，47名（5%）患有其他精神障碍或病症。根据ICD-9-CM标准对并发的医疗问题进行了系统评估和分类。患者平均患有5.6±3.1（标准差）种活动性医疗问题（范围为0至18种）。这种医疗合并症水平显著高于老年精神科门诊患者，与综合医院老年住院患者相当。在控制了年龄和教育程度的影响后，四组精神科住院患者的平均医疗问题数量没有显著差异。观察到重度抑郁症与消化系统疾病之间存在关联，这可能与外周自主神经调节异常有关。
