Gershbein L L, Baburao K, Pedroso A F
Acta Hepatogastroenterol (Stuttg). 1977 Aug;24(4):250-5.
Lipids were extracted from 28 "normal", 3 fatty and 2 cirrhotic adult livers removed at necropsy as well as from 4 newborn and infant organs. The total fatty acids were processed, the methyl esters submitted to gas chromatographic analysis and the acid differences ascertained relative to age, sex and pathology. Among other significant findings, the unsaturated acids ranged higher than the saturated homologs and were even greater in the fatty liver lipids. The latter showed an increase in 18:1 and depressions in 18:0, 22:0 and 24:0 as compared to the "normal" specimens and the same changes in 18:0 and 18:1 as contrasted to the cirrhotic lipids.
从尸检时切除的28个“正常”成人肝脏、3个脂肪肝和2个肝硬化成人肝脏以及4个新生儿和婴儿器官中提取脂质。对总脂肪酸进行处理，将甲酯进行气相色谱分析，并确定相对于年龄、性别和病理情况的酸差异。在其他重要发现中，不饱和酸的含量高于饱和同系物，在脂肪肝脂质中甚至更高。与“正常”标本相比，后者的18:1增加，18:0、22:0和24:0降低；与肝硬化脂质相比，18:0和18:1也有相同变化。
