Mokhov V M, Bliuzdin Iu A
Vopr Med Khim. 1987 May-Jun;33(3):38-42.
Fatty acid spectrum of liver tissue lipids was studied by means of gas-liquid chromatography in 58 bioptic samples from patients with chronic hepatitis, liver cirrhosis and fatty hepatosis. A statistically significant decrease in content of linoleic, arachidonic and docosahexaenic acids as well as an increase in oleic, palmitoleic and myristic acids were found. Under conditions of the diseases studied fatty acid spectrum of liver tissue lipids altered. A decrease in degree of lipid desaturation was especially distinct in liver tissue cirrhosis.
采用气液色谱法对58例慢性肝炎、肝硬化和脂肪肝患者的活检样本肝组织脂质的脂肪酸谱进行了研究。结果发现,亚油酸、花生四烯酸和二十二碳六烯酸的含量有统计学意义的下降,而油酸、棕榈油酸和肉豆蔻酸的含量增加。在所研究疾病的情况下,肝组织脂质的脂肪酸谱发生了改变。脂质去饱和程度的降低在肝组织肝硬化中尤为明显。