Robinson M J, Cobb M H
University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75235-904,1 USA.
Curr Opin Cell Biol. 1997 Apr;9(2):180-6. doi: 10.1016/s0955-0674(97)80061-0.
Nearly all cell surface receptors utilize one or more of the mitogen-activated protein kinase cascades in their repertoire of signal transduction mechanisms. Recent advances in the study of such cascades include the cloning of genes encoding novel members of the cascades, further definition of the roles of the cascades in responses to extracellular signals, and examination of cross-talk between different cascades.
几乎所有细胞表面受体在其信号转导机制中都利用一种或多种丝裂原活化蛋白激酶级联反应。此类级联反应研究的最新进展包括编码级联反应新成员的基因克隆、级联反应在细胞对细胞外信号应答中作用的进一步明确，以及不同级联反应间相互作用的研究。
