Sánchez-Yebra W, Díaz Y, Molina P, Giner P, Vitutia M M, Anda P
Servicio de Laboratorio, Hospital General Básico, Antequera, Málaga.
Enferm Infecc Microbiol Clin. 1997 Feb;15(2):77-81.
Tick-borne relapsing fever (FRGT) is a worldwide zoonosis. The disease is caused by spirochetes of the genus Borrelia, and is transmitted to man by ticks of the genus Ornithodoros (O. erraticus in Spain).
5 FRTG cases attended in our hospital in a 2 years period are described. Diagnosis was established in all cases by demonstration of borreliae in peripheral blood. Three Borrelia strains were isolated from blood of 3 of our patients and they are maintained by passages through mice.
High fever, tachycardia and headache were noted in all cases accompanied in 2 of them by hepatosplenomegaly. Three of the patients complained of arthromyalgias or lumbar myalgia. Treatment with doxycicline was curative in all of them.
FRGT incidence in our country is probably underestimated due to the low suspicion of the disease and the specificity of the clinical symptoms. The isolement of the causative Borrelia strain will allow the development of more specific serological tests necessary to establish the prevalence of this disease as well to assess its implication in chronic diseases, as is observed in other borreliosis (i.e. Lyme disease), that might be missed at this moment.
蜱传回归热(FRGT)是一种全球性人畜共患病。该疾病由疏螺旋体属的螺旋体引起,通过钝缘蜱属的蜱(在西班牙为O. erraticus)传播给人类。
描述了我院在两年期间收治的5例蜱传回归热病例。所有病例均通过在外周血中发现疏螺旋体确诊。从3例患者的血液中分离出3株疏螺旋体菌株,并通过小鼠传代进行保存。
所有病例均出现高热、心动过速和头痛,其中2例伴有肝脾肿大。3例患者主诉关节痛或腰背痛。所有患者使用强力霉素治疗均有效。
由于对该疾病的怀疑度低以及临床症状的特异性,我国蜱传回归热的发病率可能被低估。致病性疏螺旋体菌株的分离将有助于开发更具特异性的血清学检测方法,这些检测方法对于确定该疾病的流行情况以及评估其在慢性疾病中的影响是必要的,正如在其他螺旋体病(如莱姆病)中所观察到的,目前这些影响可能被忽视。