Weitzman S, Cooper L, Chambless L, Rosamond W, Clegg L, Marcucci G, Romm F, White A
Department of Biostatistics, University of North Carolina at Chapel Hill 27514, USA.
Am J Cardiol. 1997 Mar 15;79(6):722-6. doi: 10.1016/s0002-9149(96)00857-0.
This study compared rates of performance of cardiac procedures in relation to gender, race, and geographic location in patients hospitalized for myocardial infarction. The Atherosclerosis Risk in Communities (ARIC) study provides population data and standardized data collection methods. Hospital records of eligible people aged 35 to 74 years were abstracted in communities of 4 states in the United States: North Carolina, Mississippi, Maryland, and Minnesota. Between January 1987 and December 1991, 5,462 "definite" hospitalized patients with myocardial infarctions were identified. Women treated in nonteaching hospitals were less likely than men to have coronary angiography (odds ratio [OR] 0.7, 95% confidence interval [CI] 0.5 to 1.0), coronary artery bypass graft surgery (CABG) (OR 0.6, 95% CI 0.4 to 0.8), and thrombolytic therapy (OR 0.8, 95% CI 0.6 to 1.0), after controlling for age, race, severity of myocardial infarction, co-morbidity, and geographic area. Findings were similar in teaching hospitals. Blacks in the biracial communities were significantly less likely than whites to have coronary angiography, percutaneous transluminal coronary angioplasty, coronary artery bypass graft surgery, and thrombolytic therapy. After controlling for age, race, severity of myocardial infarction and co-morbidity, no consistent geographic differences were observed, except for Forsyth whites having the highest and Washington County the lowest odds for coronary angiography. Appropriate outcome measures would serve to evaluate the effect, if any, of the differences described on the ARIC population.
本研究比较了因心肌梗死住院患者在心脏手术方面的表现率与性别、种族及地理位置的关系。社区动脉粥样硬化风险(ARIC)研究提供了人口数据和标准化的数据收集方法。在美国4个州的社区抽取了年龄在35至74岁之间符合条件者的医院记录:北卡罗来纳州、密西西比州、马里兰州和明尼苏达州。在1987年1月至1991年12月期间,共识别出5462名“明确的”因心肌梗死住院患者。在控制了年龄、种族、心肌梗死严重程度、合并症和地理区域后,在非教学医院接受治疗的女性比男性接受冠状动脉造影(比值比[OR]0.7,95%置信区间[CI]0.5至1.0)、冠状动脉旁路移植术(CABG)(OR 0.6,95%CI 0.4至0.8)和溶栓治疗(OR 0.8,95%CI 0.6至1.0)的可能性更小。教学医院的结果相似。在混血社区中,黑人比白人接受冠状动脉造影、经皮腔内冠状动脉成形术、冠状动脉旁路移植术和溶栓治疗的可能性显著更小。在控制了年龄、种族、心肌梗死严重程度和合并症后,未观察到一致的地理差异,但福赛斯县的白人进行冠状动脉造影的比值最高,华盛顿县最低。适当的结果指标将有助于评估所描述的差异对ARIC人群的影响(如果有的话)。