Loss of heterozygosity for chromosome 11 in Epstein-Barr-virus associated nasopharyngeal carcinoma.
作者信息
Mutirangura A, Tanunyutthawongese C, Kerekhanjanarong V, Sriuranpong V, Pornthanakasem W, Yenrudi S, Supiyaphun P, Voravud N
机构信息
Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
出版信息
J Med Assoc Thai. 1996 Dec;79 Suppl 1:S65-70.
PMID:9071069
Abstract
In order to demonstrate and define possible tumor suppressor gene loci on chromosome 11 associated with NPC, we used 7 STR to test for LOH on 25 NPC samples. LOH was detected in 46 per cent of cases. Most LOH loci were clustered on the long arm. Further study demonstrated 22 per cent and 45.5 per cent of cases with LOH on 11q13 and 11q23 respectively.
摘要
Zotero 插件