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[肺曲霉病的外科治疗]

[Surgical treatment for pulmonary aspergillosis].

作者信息

Yamamoto H

机构信息

Division of the Thoracic Surgery, Tokyo Metropolitan Hospital of Fuchu, Japan.

出版信息

Kekkaku. 1997 Feb;72(2):125-31.

PMID:9071096
Abstract

Between 1985 and 1994, 141 patients with pulmonary aspergilloma underwent surgical treatment in 18 hospitals, which belong to Japanese Tuberculosis Research Committee. Applied surgical procedures are divided into two major categories. One is pulmonary resection variety, and the other is lung preserving or space reducing surgery. The former consists of 20 pneumonectomies, 62 lobectomies and 13 lesser operations. The latter is composed of combined mordalities of space reducing surgery (SRS) such as thoracoplasty, air-plombage, cavernoplasty and muscle plombage to reduce the cavity or the emphysematous bulla, which contains fungus balls within it. This kind of operation is applied for the patients, who have impaired lung function, strong pleural adhesion and severe complications. Triad of thoracoplasty, cavernoplasty and muscle plombage is the most frequent combination and was applied to 20 patients in this study. Operative mortality is one in pulmonary resection group and none in SRS group. Hospital deaths are two in the former and one in the latter. Success rate of operation is 95.8% in pulmonary resection, and 78.3% in SRS, especially 85.0% in the triad, mentioned above. However, SRS required a couple of additional operation on occasion to reach final success. Morbidity rate is 23.2% in pulmonary resection, and 17.4% in SRS. Thoracic empyema with or without bronchial fistula is the most common complication of the former. On the other hand, infection of the residual cavity and subcutaneus abcess are the main complications of the latter.

摘要

1985年至1994年间,141例肺曲菌球患者在隶属于日本结核病研究委员会的18家医院接受了手术治疗。所采用的手术方法分为两大类。一类是肺切除术,另一类是肺保留或减容手术。前者包括20例全肺切除术、62例肺叶切除术和13例小手术。后者由诸如胸廓成形术、空气填充术、空洞成形术和肌肉填充术等减容手术的联合术式组成,以缩小含有曲菌球的空洞或气肿性肺大疱。这类手术适用于肺功能受损、胸膜粘连严重和并发症严重的患者。胸廓成形术、空洞成形术和肌肉填充术三联术是最常用的组合,本研究中有20例患者采用了该术式。肺切除组手术死亡率为1例,减容手术组无手术死亡病例。医院死亡病例中,肺切除组有2例,减容手术组有1例。肺切除手术成功率为95.8%,减容手术成功率为78.3%,尤其是上述三联术式的成功率为85.0%。然而,减容手术有时需要额外进行几次手术才能最终成功。肺切除组的发病率为23.2%,减容手术组为17.4%。前者最常见的并发症是伴有或不伴有支气管瘘的脓胸。另一方面,后者的主要并发症是残余空洞感染和皮下脓肿。

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