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肺及支气管曲菌球的外科治疗

[Surgical treatment of pulmonary and bronchial aspergilloma].

作者信息

Massard G, Roeslin N, Wihlm J M, Dumont P, Witz J P, Morand G

机构信息

Service de Chirurgie Thoracique, CHRU, Hôpital Central, Strasbourg.

出版信息

Ann Chir. 1993;47(2):147-51.

PMID:8317873
Abstract

From 1974 to 1990, 61 patients were admitted for pulmonary (55) or bronchial (6) aspergilloma; 50 were treated by surgery. Operative treatment was mandatory because of disabling symptoms in 17 patients, rapid growth on radiological survey in 7 others, diagnostic doubt in 10 and association with bronchogenic cancer in 2. 14 were operated on in order to prevent evolutive complications. Complete resection was possible in 39 patients: with lobectomy or segmentectomy in 34 and with pleuro-pneumonectomy in 5. In 10 others, respiratory failure only allowed speleotomy and thoracoplasty. One thoracotomy was exploratory because of an associated unresectable cancer. Postoperative complications frequently occurred with pulmonary aspergilloma: 4 postoperative deaths, 33 experienced non-fatal complications (28 major bleedings, 16 rehabititation defects, 6 empyemas, 5 respiratory failures). Nevertheless, among 10 patients with either bronchial aspergilloma or pulmonary aspergilloma without underlying disease, only one had a complicated outcome. In conclusion, surgical treatment is well tolerated in the absence of underlying parenchymal disease. However, despite the major operative risk, surgery remains the only efficient treatment in symptomatic patients.

摘要

1974年至1990年期间,61例患者因肺曲菌球(55例)或支气管曲菌球(6例)入院;50例接受了手术治疗。17例患者因症状严重而必须进行手术治疗,7例因影像学检查显示病变快速生长,10例因诊断存疑,2例因合并支气管源性癌。14例进行手术是为了预防病情进展引发的并发症。39例患者实现了完整切除:34例行肺叶切除术或肺段切除术,5例行胸膜全肺切除术。另外10例患者因呼吸衰竭仅接受了病灶清除术和胸廓成形术。1例开胸手术是因为合并无法切除的癌症而进行探查。肺曲菌球手术后并发症频发:4例术后死亡,33例出现非致命性并发症(28例大出血、16例修复缺陷、6例脓胸、5例呼吸衰竭)。然而,在10例支气管曲菌球或无基础疾病的肺曲菌球患者中,只有1例出现了复杂的结局。总之,在没有潜在实质性疾病的情况下,手术治疗耐受性良好。然而,尽管手术风险很大,但手术仍然是有症状患者唯一有效的治疗方法。

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