Uvnäs-Moberg K
Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.
Ann N Y Acad Sci. 1997 Jan 15;807:146-63. doi: 10.1111/j.1749-6632.1997.tb51917.x.
Nonnoxious sensory stimulation associated with friendly social interaction induces a psychophysiological response pattern involving sedation, relaxation, decreased sympathoadrenal activity, and increased vagal nerve tone and thereby an endocrine and metabolic pattern favoring the storage of nutrients and growth. It is suggested that oxytocin released from parvocellular neurons in the paraventricular nucleus (PVN) in response to nonnoxious stimulation integrates this response pattern at the hypothalamic level. The response pattern just described characterized by calm, relaxation, and anabolic metabolism could be regarded as an antithesis to the well known fight-flight response in which mental activation, locomotor activity, and catabolic metabolism are expressed. Furthermore, the health-promoting aspect of friendly and supportive relationships might be a consequence of repetitive exposure to nonnoxious sensory stimulation causing the physiological endocrine and behavioral changes just described.
与友好社交互动相关的无害感觉刺激会引发一种心理生理反应模式，包括镇静、放松、交感肾上腺活动减少、迷走神经张力增加，从而形成一种有利于营养储存和生长的内分泌和代谢模式。有人认为，室旁核（PVN）小细胞神经元在受到无害刺激时释放的催产素在下丘脑水平整合了这种反应模式。刚刚描述的以平静、放松和合成代谢代谢为特征的反应模式，可以被视为与众所周知的战斗-逃跑反应的对立面，在战斗-逃跑反应中会表现出精神激活、运动活动和分解代谢代谢。此外，友好和支持性人际关系对健康有益的方面，可能是反复接触无害感觉刺激导致上述生理内分泌和行为变化的结果。
