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[老年患者乳糜泻的诊断:一例临床病例描述]

[Diagnosis of celiac disease in an elderly subject: description of a clinical case].

作者信息

Monti M A, Negri E, Paina S, Secchi G C

机构信息

Divisione di Medicina Generale, Università degli Studi di Milano.

出版信息

Ann Ital Med Int. 1996 Oct-Dec;11(4):284-7.

PMID:9072071
Abstract

A 70-year-old woman was admitted to the hospital because of a 5-year history of weight loss, weakness, anemia, osteomalacia, pathologic fractures and pain responding only to narcotic analgesics. A diagnosis of celiac disease was made on the basis of pathologic xylose absorption test results, studies confirming the presence of antigliadin and antiendomysial antibodies, and jejunal biopsy evidencing shortened or absent villi. The detection of unusual cases of celiac disease without diarrhea is on the increase. The only observable symptoms of this pathology may be osteomalacia or persistent iron deficiency anemia despite oral iron therapy.

摘要

一名70岁女性因有5年体重减轻、乏力、贫血、骨软化、病理性骨折及仅对麻醉性镇痛药有效的疼痛病史而入院。根据木糖吸收试验病理结果、证实存在抗麦胶蛋白和抗肌内膜抗体的研究以及空肠活检显示绒毛缩短或缺失,诊断为乳糜泻。无腹泻的乳糜泻罕见病例的检出率正在上升。这种疾病唯一可观察到的症状可能是骨软化或尽管进行了口服铁剂治疗仍持续存在的缺铁性贫血。

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