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[老年患者乳糜泻的诊断:一例临床病例描述]

[Diagnosis of celiac disease in an elderly subject: description of a clinical case].

作者信息

Monti M A, Negri E, Paina S, Secchi G C

机构信息

Divisione di Medicina Generale, Università degli Studi di Milano.

出版信息

Ann Ital Med Int. 1996 Oct-Dec;11(4):284-7.

PMID:9072071
Abstract

A 70-year-old woman was admitted to the hospital because of a 5-year history of weight loss, weakness, anemia, osteomalacia, pathologic fractures and pain responding only to narcotic analgesics. A diagnosis of celiac disease was made on the basis of pathologic xylose absorption test results, studies confirming the presence of antigliadin and antiendomysial antibodies, and jejunal biopsy evidencing shortened or absent villi. The detection of unusual cases of celiac disease without diarrhea is on the increase. The only observable symptoms of this pathology may be osteomalacia or persistent iron deficiency anemia despite oral iron therapy.

摘要

一名70岁女性因有5年体重减轻、乏力、贫血、骨软化、病理性骨折及仅对麻醉性镇痛药有效的疼痛病史而入院。根据木糖吸收试验病理结果、证实存在抗麦胶蛋白和抗肌内膜抗体的研究以及空肠活检显示绒毛缩短或缺失,诊断为乳糜泻。无腹泻的乳糜泻罕见病例的检出率正在上升。这种疾病唯一可观察到的症状可能是骨软化或尽管进行了口服铁剂治疗仍持续存在的缺铁性贫血。

相似文献

1
[Diagnosis of celiac disease in an elderly subject: description of a clinical case].[老年患者乳糜泻的诊断:一例临床病例描述]
Ann Ital Med Int. 1996 Oct-Dec;11(4):284-7.
2
[Celiac disease in the elderly: a case report].[老年乳糜泻:一例报告]
Ann Ital Med Int. 2005 Oct-Dec;20(4):253-7.
3
Prevalence of celiac disease, Helicobacter pylori and gastroesophageal reflux in patients with refractory iron deficiency anemia.难治性缺铁性贫血患者中乳糜泻、幽门螺杆菌及胃食管反流的患病率
J Trop Pediatr. 2008 Feb;54(1):43-53. doi: 10.1093/tropej/fmm080. Epub 2007 Sep 30.
4
Isolated iron deficiency: an atypical manifestation of celiac disease.
J Fam Pract. 1995 Jan;40(1):89-91.
5
[Severe osteomalacia in endemic sprue. An important differential diagnosis in osteoporosis].
Fortschr Med. 1998 Mar 20;116(8):42-5.
6
[Overlooked celiac disease in a 59-year old woman with severe osteomalacia].
Ugeskr Laeger. 2000 Jan 31;162(5):670-1.
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[Association of asymptomatic celiac disease and Crohn's disease].无症状性乳糜泻与克罗恩病的关联
Ann Med Interne (Paris). 2000 Sep;151(5):411-2.
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Clinical presentation of adult celiac disease in Western Saudi Arabia.沙特阿拉伯西部成人乳糜泻的临床表现
Saudi Med J. 2002 Dec;23(12):1514-7.
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[Hypochromic microcytic anemia as the only manifestation of celiac disease].
Rev Gastroenterol Mex. 2000 Apr-Jun;65(2):85-8.
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[Endemic celiac sprue and Hodgkin's disease in a 72-year-old patient].[一名72岁患者的地方性乳糜泻和霍奇金淋巴瘤]
Dtsch Med Wochenschr. 2002 Sep 6;127(36):1815-8. doi: 10.1055/s-2002-33869.

引用本文的文献

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Celiac disease causing severe osteomalacia: an association still present in Morocco!乳糜泻导致严重骨软化症:摩洛哥仍存在这种关联!
Pan Afr Med J. 2014 Sep 19;19:43. doi: 10.11604/pamj.2014.19.43.2757. eCollection 2014.
2
Osteomalacia associated with cutaneous psoriasis as the presenting feature of coeliac disease: a case report.以骨软化症合并皮肤银屑病为首发表现的乳糜泻:一例报告
Pan Afr Med J. 2012;11:58. Epub 2012 Mar 27.
3
Severe osteomalacia due to undiagnosed coeliac disease: three case reports of Tunisian women.未确诊的乳糜泻所致严重骨软化症:3例突尼斯女性病例报告
Rheumatol Int. 2006 Jan;26(3):261-3. doi: 10.1007/s00296-005-0618-6. Epub 2005 Jun 24.