Dubinina O N, Galeeva L R, Trubnikova L I, Varlamova T I, Tkacheva S G
Med Tr Prom Ekol. 1997(1):38-41.
The present MAC for ethylenediamine (2 mg/cu m) does not match up-to-date requirements of industrial medicine and requires experimental analysis. Using contemporary methodic approaches, the authors studied toxicodynamics of ethylenediamine, revealed parameters of its toxicity and jeopardy. Biologic effects of ethylenediamine are irritation, allergic signs and changes in central nervous system. Chronic inhalation experiment helped to determine the MAC for ethylenediamine at 0.3 mg/cu m, 2nd jeopardy grade, that requires labels "Allergen" and "Skin protection required".
目前乙二胺的最高容许浓度(2毫克/立方米)不符合工业医学的最新要求,需要进行实验分析。作者采用当代方法研究了乙二胺的毒理学,揭示了其毒性和危害参数。乙二胺的生物学效应包括刺激、过敏症状和中枢神经系统变化。慢性吸入实验有助于确定乙二胺的最高容许浓度为0.3毫克/立方米,危险等级为二级,这需要标注“过敏原”和“需皮肤防护”。