Komissarenko I V, Slavnov V N, Markov V V, Demchenko N P, Kvacheniuk A N, Kovalenko A E
Lik Sprava. 1996 Jul-Sep(7-9):70-4.
Results are submitted of studying the function of the kidneys in 34 patients with Itsenko [correction of Icenko]-Cushing disease and syndrome, who were evaluated by dynamic renoscintigraphy besides routine clinical procedures. Dynamic renoscintigraphy was found to be an important diagnostic acid enabling one to disclose function disorders of the kidneys in the preclinical stage under normal routine investigations. In this setting, there have been revealed disturbances both in secretory-filtrational and excretory and aggregate functions of the kidneys practically in all the patients irrespective of the type of hypercorticoidism. Surgical treatment of hypercorticoidism does not lead to normalization of the function of the kidneys. And what is more, function disorders of the kidney on the side of the surgical intervention appear to be even more serious.
报告了对34例伊钦科[纠正为伊琴科]-库欣病和综合征患者肾脏功能的研究结果，这些患者除了接受常规临床检查外，还通过动态肾闪烁显像进行评估。发现动态肾闪烁显像是一种重要的诊断方法，能够在常规检查正常的临床前期阶段发现肾脏功能障碍。在这种情况下，实际上所有患者无论皮质醇增多症的类型如何，其肾脏的分泌-滤过、排泄和总体功能均出现紊乱。皮质醇增多症的手术治疗并不能使肾脏功能恢复正常。而且，手术干预一侧的肾脏功能障碍似乎更为严重。
