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[糖尿病患者抗氧化系统紊乱及其恢复正常的方法]

[Antioxidant system disorder in diabetic patients and the means for its normalization].

作者信息

Zelins'kyĭ B O, Palamarchuk A V

出版信息

Lik Sprava. 1996 Jul-Sep(7-9):99-102.

PMID:9072282
Abstract

The condition was studied on the antioxidant system (AOS)--the activities of catalase, concentration of tocoferoli and reduced glutathione--in 112 patients with type I diabetes mellitus during the course of treatment. It has been established that in decompensation of diabetes mellitus there is a striking deterioration of AOS the degree of which depends upon duration and severity of the illness as well as the presence of angiopathies. Employment in the combined treatment of the donator of sulphhydric groups unithiol and a naturally occurring antioxidant tocopheroli promoted normalization of parameters associated with AOS, diabetic angiopathies included.

摘要

对112例I型糖尿病患者在治疗过程中的抗氧化系统(AOS)——过氧化氢酶活性、生育酚浓度和还原型谷胱甘肽——进行了研究。已确定在糖尿病失代偿期,AOS显著恶化,其程度取决于疾病的持续时间和严重程度以及血管病变的存在。在联合治疗中使用巯基供体二硫丙醇和天然抗氧化剂生育酚可促进与AOS相关参数(包括糖尿病血管病变)的正常化。

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