Cardi M, Muttillo I A, Amadori L, Petroni R, Mingazzini P, Barillari P, Lisi D, Bolognese A
I Instituto di Clinica Chirurgica, Dipartimento Biopatologia Umana, Cattedra Gastroenterologia, Università La Sapienza di Roma, Italy.
Dig Dis Sci. 1997 Mar;42(3):546-8. doi: 10.1023/a:1018895009305.
The aim of the study was to compare the results of ultrasonography (US) and laparoscopy in a series of 210 patients referred to our institution for the diagnosis of widespread liver diseases. Among 205 patients, laparoscopy revealed cirrhosis in 114, chronic widespread disease in 70 (chronic persistent hepatitis in 21, chronic active hepatitis in 28, steatosis in 14, acute hepatitis in 5, fibrosis in 2), and absence of liver disease in 21. Four of these cases had minor complications. A corroborative diagnosis was obtained in 122 patients (59.5%). Overall sensitivity of US was 84% with a low specificity due to the high rate of false negatives. From the results of this study we conclude that laparoscopy is a safe and essential diagnostic tool in the final diagnosis of widespread liver diseases and that US is not a reliable screening method because of its incidence of false negatives.
本研究的目的是比较超声检查（US）和腹腔镜检查在210例因广泛肝脏疾病转诊至我院进行诊断的患者中的结果。在205例患者中，腹腔镜检查显示114例为肝硬化，70例为慢性广泛性疾病（21例为慢性持续性肝炎，28例为慢性活动性肝炎，14例为脂肪变性，5例为急性肝炎，2例为纤维化），21例无肝脏疾病。其中4例出现轻微并发症。122例患者（59.5%）获得了确诊。超声检查的总体敏感性为84%，但由于假阴性率高，特异性较低。从本研究结果我们得出结论，腹腔镜检查是广泛肝脏疾病最终诊断中一种安全且必不可少的诊断工具，而超声检查由于其假阴性发生率，不是一种可靠的筛查方法。
