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新恩actin,一种增强多烯类抗真菌抗生素作用的新型抗真菌抗生素。II. 产生菌的分类学研究以及博来霉素类和链丝菌素样抗生素的同时产生。

Neo-enactin, a new antifungal antibiotic potentiating polyene antifungal antibiotics. II. Taxonomic studies of the producing microorganism and simultaneous production of bleomycin group and streptothricin-like antibiotics.

作者信息

Otani T, Ishimaru K, Kawakami Y, Yoshiyama H, Kondo H, Nakamura S

出版信息

Jpn J Antibiot. 1979 Jul;32(7):720-8.

PMID:90741
Abstract

A new antifungal antibiotic, named neo-enactin, was produced mainly in the mycelia of strain H 829-MY 10. Strain H 829-MY 10 was identified as a Streptoverticillium, determined to be nonchromogenic, and fits in the white color-series. Although Streptoverticillium olivoreticuli is known to be chromogenic, strain H 829-MY 10 is most related to that species. Thus, strain H 829-MY 10 is named as Streptoverticillium olivoreticuli subsp. neoenacticus. Besides neo-enactin, two bleomycin-group antibiotics and two streptothricin-like antibiotics were simultaneously produced by strain H 829-MY 10.

摘要

一种名为新制霉菌素的新型抗真菌抗生素主要产生于菌株H 829-MY 10的菌丝体中。菌株H 829-MY 10被鉴定为轮枝链霉菌,确定为非产色型,属于白色类群。虽然已知橄榄色轮枝链霉菌是产色型的,但菌株H 829-MY 10与该物种关系最为密切。因此,菌株H 829-MY 10被命名为橄榄色轮枝链霉菌新制霉菌素亚种。除新制霉菌素外,菌株H 829-MY 10还同时产生了两种博来霉素类抗生素和两种链丝菌素样抗生素。

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