García-Sánchez C, Estévez-González A, Suárez-Romero E, Junqué C
Service of Neurology, Santa Creu i Sant Pau Hospital, Autonomous University of Barcelona, Spain.
J Child Neurol. 1997 Feb;12(2):107-15. doi: 10.1177/088307389701200207.
The attention-deficit disorder, with and without hyperactivity, is associated with defective attention, response inhibition and, in attention-deficit disorder with hyperactivity, with motor restlessness. In adults, inattention, defective response inhibition, and impersistence are more commonly seen in right hemisphere lesions. In the present study, we investigate possible right hemisphere dysfunctions in attention-deficit disorder with hyperactivity and attention-deficit disorder without hyperactivity. The right hemisphere performance of 60 teenagers, 16 having attention-deficit disorder with hyperactivity, 9 having attention-deficit disorder without hyperactivity, and 35 controls, selected clinically (DSM-III) and experimentally (through Continuous Performance Test and Paced Auditory Addition Task), with normal IQ was assessed using a wide-ranging battery of visuospatial, visuoperceptive, and visuoconstructive functions (Benton's Line Orientation, Benton's Visual Retention, Raven's Progressive Matrices, Wechsler Adult Intelligence Scale [WAIS] Block-Design, Rey's Complex Figure). Teenagers with attention-deficit disorder with and without hyperactivity performed significantly worse than controls. Greater differences were found between subjects with attention-deficit disorder without hyperactivity and control than between subjects with attention-deficit disorder with hyperactivity and control subjects. Our results seem to be consistent with right-hemisphere dysfunction, especially in subjects with attention-deficit disorder without hyperactivity. Additionally, WAIS Block-Design and Benton's Line Orientation are the visuospatial tests with the highest discriminant power to differentiate between controls, subjects with attention-deficit disorder without hyperactivity, and subjects with attention-deficit disorder with hyperactivity.
注意力缺陷障碍，伴或不伴多动，与注意力缺陷、反应抑制有关，在伴多动的注意力缺陷障碍中还与运动性不安有关。在成年人中，注意力不集中、反应抑制缺陷和缺乏坚持性在右半球病变中更为常见。在本研究中，我们调查了伴多动的注意力缺陷障碍和不伴多动的注意力缺陷障碍中可能存在的右半球功能障碍。选取了60名青少年，其中16名患有伴多动的注意力缺陷障碍，9名患有不伴多动的注意力缺陷障碍，35名作为对照，通过临床（DSM-III）和实验（通过连续性能测试和听觉加法任务）选取，智商正常，使用一系列广泛的视觉空间、视觉感知和视觉构建功能测试（本顿线方向测试、本顿视觉保持测试、瑞文渐进矩阵测试）对其右半球功能进行评估。患有伴多动和不伴多动的注意力缺陷障碍的青少年表现明显比对照组差。与患有伴多动的注意力缺陷障碍的受试者和对照组相比，患有不伴多动的注意力缺陷障碍的受试者与对照组之间的差异更大。我们的结果似乎与右半球功能障碍一致，尤其是在患有不伴多动的注意力缺陷障碍的受试者中。此外，韦氏成人智力量表积木设计测试和本顿线方向测试是区分对照组、患有不伴多动的注意力缺陷障碍的受试者和患有伴多动的注意力缺陷障碍的受试者的判别能力最高的视觉空间测试。
