Pine D A, Madlon-Kay D J, Sauser M
Department of Family Practice, Park Nicollet Medical Center, Minneapolis, MN, USA.
Arch Fam Med. 1997 Mar-Apr;6(2):129-34. doi: 10.1001/archfami.6.2.129.
To evaluate the effect of a nurse-based intervention for patients with high total cholesterol (TC) levels in a community practice.
Clinical trial without a control followed by a nonrandomized control trial.
Suburban primary care practice.
White patients with TC higher than 6.21 mmol/L (240 mg/dL). In the initial trial, 82 patients with a mean TC level of 6.80 mmol/L (263 mg/dL). Fifty-three preponderantly female patients in the nonrandomized control trial with a mean TC level of 6.83 mmol/L (264 mg/dL).
Counseling by office nurses using the Eating Pattern Assessment Tool and handouts with brand-specific food advice. In the initial study, patients attended up to 5 nurse counseling visits. In a follow-up study, intervention patients attending 2 or more counseling sessions were matched with other patients in the practice.
Eating Pattern Assessment Tool scores in the initial study and TC levels in both trials.
Mean Eating Pattern Assessment Tool scores at baseline in both studies demonstrated that intervention patients were already following a diet consistent with the National Cholesterol Education Program Step I Diet. In the initial study, mean TC levels of the patients declined 2% (P < .05) and mean Eating Pattern Assessment Tool score improved from 23.4 to 20.4 (P < .001). In the follow-up study, the mean TC level of all patients improved significantly (P = .002). However, the improvement of the intervention patients was no better than that of the comparison patients.
The nurse counseling intervention was not effective in patients already following a Step I Diet.
评估在社区医疗实践中,针对总胆固醇(TC)水平高的患者开展的以护士为主导的干预措施的效果。
无对照的临床试验,随后进行非随机对照试验。
郊区初级保健机构。
TC高于6.21毫摩尔/升(240毫克/分升)的白人患者。在初始试验中,82名患者的平均TC水平为6.80毫摩尔/升(263毫克/分升)。在非随机对照试验中,53名以女性为主的患者,平均TC水平为6.83毫摩尔/升(264毫克/分升)。
办公室护士使用饮食模式评估工具并发放特定品牌食物建议手册进行咨询。在初始研究中,患者最多接受5次护士咨询。在后续研究中,参加2次或更多咨询会议的干预组患者与该医疗机构的其他患者进行匹配。
初始研究中的饮食模式评估工具得分,以及两项试验中的TC水平。
两项研究中基线时的平均饮食模式评估工具得分表明,干预组患者已经遵循与国家胆固醇教育计划第一步饮食一致的饮食。在初始研究中,患者的平均TC水平下降了2%(P <.05),平均饮食模式评估工具得分从23.4提高到20.4(P <.001)。在后续研究中,所有患者的平均TC水平均有显著改善(P =.002)。然而,干预组患者的改善情况并不比对照组患者更好。
对于已经遵循第一步饮食的患者,护士咨询干预措施无效。