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体外受精和胚胎移植后光滑念珠菌性绒毛膜羊膜炎

Candida glabrata chorioamnionitis following in vitro fertilization and embryo transfer.

作者信息

Sfameni S F, Talbot J M, Chow S L, Brenton L A, Scurry J P

机构信息

University of Melbourne, Department of Obstetrics and Gyneacology, Mercy Hospital for Women, East Melbourne, Victoria.

出版信息

Aust N Z J Obstet Gynaecol. 1997 Feb;37(1):88-91. doi: 10.1111/j.1479-828x.1997.tb02225.x.

DOI:10.1111/j.1479-828x.1997.tb02225.x
PMID:9075555
Abstract

Candida glabrata is a yeast which is considered to be a commensal of the vagina with limited pathogenicity in the immunocompetent host. We report 2 cases of severe chorioamnionitis occurring in pregnancies achieved by in vitro fertilization techniques which resulted in preterm delivery and pregnancy loss. Candida glabrata as the causative agent was probably introduced into the uterus by the cannula at the time of embryo transfer. It is recommended that appropriate investigation of the microbial flora of the cervix be undertaken and treatment instituted prior to embryo transfer in order to prevent this complication.

摘要

光滑念珠菌是一种酵母菌,在免疫功能正常的宿主中,它被认为是阴道内的共生菌,致病性有限。我们报告了2例体外受精技术妊娠中发生的严重绒毛膜羊膜炎病例,这导致了早产和妊娠丢失。光滑念珠菌作为病原体可能在胚胎移植时通过插管被引入子宫。建议在胚胎移植前对宫颈微生物群进行适当检查并进行治疗,以预防这种并发症。

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J Matern Fetal Neonatal Med. 2019 May;32(10):1703-1720. doi: 10.1080/14767058.2017.1416083. Epub 2017 Dec 27.
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Vulvovaginal candidiasis in pregnancy.妊娠期外阴阴道念珠菌病
Curr Infect Dis Rep. 2015 Jun;17(6):462. doi: 10.1007/s11908-015-0462-0.
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Severe systemic candidiasis following immunomodulation therapy in in vitro fertilisation-embryo transfer (IVF-ET).体外受精-胚胎移植(IVF-ET)免疫调节治疗后发生的严重全身性念珠菌病。
BMJ Case Rep. 2014 Mar 31;2014:bcr2013203202. doi: 10.1136/bcr-2013-203202.
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