• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

曲安奈德可改善克罗恩病狭窄的治疗效果。

Triamcinolone improves outcome in Crohn's disease strictures.

作者信息

Lavy A

机构信息

Gastroenterology Unit, Rambam Medical Center, Haifa, Israel.

出版信息

Dis Colon Rectum. 1997 Feb;40(2):184-6. doi: 10.1007/BF02054985.

DOI:10.1007/BF02054985
PMID:9075754
Abstract

PURPOSE

This study was undertaken to examine the effect of local injection of potent steroids on recurrence of Crohn's disease strictures.

METHODS

Ten patients with colonic strictures attributable to Crohn's disease were treated by dilation and injection of triamcinolone. Five of them had postoperative strictures.

RESULTS

Patients were followed for 1.5 to 3 years. Two patients required additional dilation and injection of steroids after one year. Eight patients remained well.

CONCLUSION

Local injection of steroids improves outcome in strictures caused by Crohn's disease.

摘要

目的

本研究旨在探讨局部注射强效类固醇对克罗恩病狭窄复发的影响。

方法

10例因克罗恩病导致结肠狭窄的患者接受了扩张及曲安奈德注射治疗。其中5例为术后狭窄。

结果

患者随访1.5至3年。2例患者在1年后需要再次进行扩张及类固醇注射。8例患者情况良好。

结论

局部注射类固醇可改善克罗恩病所致狭窄的治疗效果。

相似文献

1
Triamcinolone improves outcome in Crohn's disease strictures.曲安奈德可改善克罗恩病狭窄的治疗效果。
Dis Colon Rectum. 1997 Feb;40(2):184-6. doi: 10.1007/BF02054985.
2
Endoscopic balloon dilation of Crohn's disease strictures-safety, efficacy and clinical impact.克罗恩病狭窄的内镜球囊扩张术-安全性、疗效和临床影响。
World J Gastroenterol. 2017 Nov 7;23(41):7397-7406. doi: 10.3748/wjg.v23.i41.7397.
3
Long-acting steroid injection after endoscopic dilation of anastomotic Crohn's strictures may improve the outcome: a retrospective case series.内镜扩张克罗恩病吻合口狭窄后注射长效类固醇可能改善预后:一项回顾性病例系列研究。
Endoscopy. 2003 Apr;35(4):333-7. doi: 10.1055/s-2003-38145.
4
Endoscopic Dilatation of Crohn's Anastomotic Strictures is Effective in the Long Term, and Escalation of Medical Therapy Improves Outcomes in the Biologic Era.克罗恩病吻合口狭窄的内镜扩张术长期有效,在生物制剂时代强化药物治疗可改善治疗效果。
J Crohns Colitis. 2016 Oct;10(10):1172-8. doi: 10.1093/ecco-jcc/jjw072. Epub 2016 Mar 12.
5
A pilot study of intrastricture steroid versus placebo injection after balloon dilatation of Crohn's strictures.克罗恩狭窄气囊扩张术后狭窄内注射类固醇与安慰剂的一项初步研究。
Clin Gastroenterol Hepatol. 2007 Sep;5(9):1065-9. doi: 10.1016/j.cgh.2007.04.013. Epub 2007 Jul 12.
6
Steroid injection improves outcome in Crohn's disease strictures.类固醇注射可改善克罗恩病狭窄的治疗效果。
Endoscopy. 1994 May;26(4):366. doi: 10.1055/s-2007-1008995.
7
Balloon dilatation with or without intralesional and oral corticosteroids for anastomotic Crohn's disease strictures.
J Gastrointestin Liver Dis. 2015 Dec;24(4):537-9. doi: 10.15403/jgld.2014.1121.244.hav.
8
Endoscopic balloon dilation in the management of strictures in Crohn's disease: a systematic review and meta-analysis of non-randomized trials.内镜下球囊扩张术治疗克罗恩病狭窄:非随机试验的系统评价和荟萃分析
Surg Endosc. 2016 Dec;30(12):5434-5443. doi: 10.1007/s00464-016-4902-1. Epub 2016 Apr 28.
9
Endoscopic balloon dilatation as a therapeutic option in the management of intestinal strictures resulting from Crohn's disease.内镜下球囊扩张术作为克罗恩病所致肠道狭窄治疗的一种选择。
Br J Surg. 1991 Apr;78(4):453-4. doi: 10.1002/bjs.1800780421.
10
Endoscopic balloon dilation of colonic and ileo-colonic Crohn's strictures: long-term results.结肠和回结肠克罗恩狭窄的内镜下球囊扩张:长期结果
Gastrointest Endosc. 1992 Mar-Apr;38(2):142-7. doi: 10.1016/s0016-5107(92)70379-4.

引用本文的文献

1
Fibrostenosing Crohn's Disease: Pathogenetic Mechanisms and New Therapeutic Horizons.纤维狭窄型克罗恩病:发病机制和新的治疗前景。
Int J Mol Sci. 2024 Jun 7;25(12):6326. doi: 10.3390/ijms25126326.
2
Insulated tip/needle-knife endoscopic stricturotomy is safe and effective for treatment of non-traversable anorectal strictures.绝缘头/针刀内镜下狭窄切开术治疗不可贯通性肛管直肠狭窄安全有效。
Endosc Int Open. 2024 Feb 15;12(2):E231-E236. doi: 10.1055/a-2230-7372. eCollection 2024 Feb.
3
Review on Advances in Pediatric Endoscopy in the Management of Inflammatory Bowel Disease.
小儿内镜在炎症性肠病管理中的进展综述
Curr Pediatr Rev. 2025;21(2):154-165. doi: 10.2174/0115733963268547231128101929.
4
Endoscopic Management of Benign Colonic Obstruction and Pseudo-Obstruction.良性结肠梗阻和假性梗阻的内镜治疗
Clin Endosc. 2020 Jan;53(1):18-28. doi: 10.5946/ce.2019.058. Epub 2019 Oct 24.
5
Review of the use of intralesional steroid injections in the management of ileocolonic Crohn's strictures.瘤内注射类固醇在回结肠型克罗恩病狭窄治疗中的应用综述。
Frontline Gastroenterol. 2013 Oct;4(4):238-243. doi: 10.1136/flgastro-2012-100297. Epub 2013 Mar 27.
6
Crohn's disease complicated by strictures: a systematic review.克罗恩病并发狭窄:系统评价。
Gut. 2013 Jul;62(7):1072-84. doi: 10.1136/gutjnl-2012-304353. Epub 2013 Apr 26.
7
Intralesional steroid injection therapy in the management of resistant gastrointestinal strictures.病灶内注射类固醇疗法用于治疗难治性胃肠道狭窄
World J Gastrointest Endosc. 2010 Feb 16;2(2):61-8. doi: 10.4253/wjge.v2.i2.61.
8
Balloon dilation and intralesional steroid for benign rectal stricture management in a cat.猫良性直肠狭窄管理中球囊扩张及病灶内注射类固醇治疗
J Feline Med Surg. 2010 Aug;12(8):663-5. doi: 10.1016/j.jfms.2010.04.008. Epub 2010 Jul 4.
9
Long-term results of endoscopic balloon dilatation of lower gastrointestinal tract strictures in Crohn's disease: a prospective study.克罗恩病下消化道狭窄内镜下球囊扩张术的长期疗效:一项前瞻性研究
World J Gastroenterol. 2009 Jun 7;15(21):2623-7. doi: 10.3748/wjg.15.2623.
10
Through the endoscope balloon dilation of ileocolonic strictures: prognostic factors, complications, and effectiveness.经内镜球囊扩张治疗回结肠狭窄:预后因素、并发症及疗效
Int J Colorectal Dis. 2008 Jul;23(7):689-96. doi: 10.1007/s00384-008-0461-9. Epub 2008 Mar 13.