Kingham J G, Swain P, Swarbrick E T, Walker J G, Dawson A M
Lancet. 1979 Sep 29;2(8144):662-4. doi: 10.1016/s0140-6736(79)92066-x.
Severe hypoalbuminaemia developed in two patients on long-term dapsone treatment for dermatitis herpetiformis. The patients had been treated with dapsone for 3 and 11 years before the syndrome developed and both recovered completely when dapsone was withdrawn. Albumin-turnover studies revealed a great increase in intravascular albumin catabolism and a modest decrease in synthesis.
两名长期服用氨苯砜治疗疱疹样皮炎的患者出现了严重低白蛋白血症。在该综合征出现前，这两名患者已接受氨苯砜治疗3年和11年，停用氨苯砜后两人均完全康复。白蛋白转换研究显示，血管内白蛋白分解代谢大幅增加，合成略有减少。
