Chung S M, Lee A G, Holds J B, Roper-Hall G, Cruz O A
Anheuser Busch Eye Institute, St Louis University School of Medicine, Mo, USA.
Arch Ophthalmol. 1997 Mar;115(3):365-70. doi: 10.1001/archopht.1997.01100150367009.
To describe 2 patients with ocular neuromyotonia in association with Graves orbitopathy and to consider the possible underlying mechanisms.
Description of the clinical findings in 2 patients with these conditions.
Neuro-ophthalmology referral centers.
Two patients, aged 55 and 52 years, had episodic, involuntary periods of vertical diplopia and dysthyroid orbitopathy.
Treatment with carbamazepine in one patient and external beam radiation therapy in the second patient.
Frequency and duration of episodic spasms of the extraocular muscles.
Although radiation therapy is the most common association with ocular neuromyotonia, it cannot explain the involuntary contractions of extraocular muscles in all affected patients. Other mechanisms must be involved, such as those discussed in this article.
Ocular neuromyotonia is described in 2 patients with dysthyroid orbitopathy, confirming previous findings. Possible mechanisms are given.
描述2例伴有格雷夫斯眼眶病的眼性眼肌阵挛患者，并探讨其可能的潜在机制。
对2例患有这些病症患者的临床发现进行描述。
神经眼科转诊中心。
两名患者，年龄分别为55岁和52岁，有发作性、非自主性垂直复视和甲状腺功能障碍性眼眶病。
一名患者接受卡马西平治疗，另一名患者接受外照射放疗。
眼外肌发作性痉挛的频率和持续时间。
虽然放疗是与眼性眼肌阵挛最常见的关联因素，但它不能解释所有受影响患者眼外肌的非自主性收缩。必须涉及其他机制，如本文所讨论的机制。
描述了2例甲状腺功能障碍性眼眶病患者的眼性眼肌阵挛，证实了先前的发现。并给出了可能的机制。
