Douard H, Chevalier L, Labbe L, Choussat A, Broustet J P
Hôpital Cardiologique du Haut Lévèque, Pessac, France.
Eur Heart J. 1997 Mar;18(3):464-9. doi: 10.1093/oxfordjournals.eurheartj.a015267.
Haemodynamic measurements taken at rest and during exercise showed that percutaneous transvenous mitral commissurotomy results in both acute and long-term improvement. However, the time lag before there is an increase in exercise and in peak oxygen uptake appears to be delayed and irregular.
To assess the potential of physical training to restore better physical capacity after percutaneous transvenous mitral commissurotomy, 26 patients with mitral stenosis were studied after the procedure. The group was split into two. Thirteen underwent a 3-month rehabilitation programme, and the other 13, who did not, acted as controls.
The mitral valve orifice area increased similarly, from 1.12 +/- 0.17 to 1.88 +/- 0.28 cm2 in the training group and from 1.04 +/- 0.16 to 1.88 +/- 0.19 cm2 in the control group. Cardiopulmonary parameters were similar before percutaneous transvenous mitral commissurotomy (peak VO2: 19.9 +/- 2.4 vs 18.9 +/- 4.5 ml. min-1.kg-1; peak workload: 94.6 +/- 29.3 vs 96.1 +/- 25 watts; VO2 at anaerobic threshold: 17 +/- 3.4 vs 16.1 +/- 5.2 ml.min-1.kg-1; all P = ns). Three months later the results were higher in the training group 1 (peak VO2: 26.6 +/- 4.7 vs 21.6 +/- 3.8 ml.min-1.kg-1, P = 0.03; peak workload: 125.4 +/- 26.6 vs 108.5 +/- 23 watts, P = 0.03; VO2 at anaerobic threshold: 19.6 +/- 5.8 vs 15.8 +/- 2.9 ml.min-1.kg-1; P = 0.02).
These results indicate that patients should take up exercise after successful percutaneous transvenous mitral commissurotomy for better functional improvement.
静息和运动时的血流动力学测量显示,经皮经静脉二尖瓣交界切开术可带来急性和长期的改善。然而,运动增加和峰值摄氧量增加之前的时间延迟似乎是延迟且不规律的。
为评估体育训练在经皮经静脉二尖瓣交界切开术后恢复更好身体能力的潜力,对26例二尖瓣狭窄患者在手术后进行了研究。该组患者分为两组。13例接受了为期3个月的康复计划,另外13例未接受康复计划,作为对照组。
二尖瓣口面积增加情况相似,训练组从1.12±0.17平方厘米增加到1.88±0.28平方厘米,对照组从1.04±0.16平方厘米增加到1.88±0.19平方厘米。经皮经静脉二尖瓣交界切开术前心肺参数相似(峰值摄氧量:19.9±2.4对18.9±4.5毫升·分钟-1·千克-1;峰值工作量:94.6±29.3对96.1±25瓦;无氧阈时的摄氧量:17±3.4对16.1±5.2毫升·分钟-1·千克-1;所有P值均无统计学意义)。三个月后,训练组1的结果更高(峰值摄氧量:26.6±4.7对21.6±3.8毫升·分钟-1·千克-1,P = 0.03;峰值工作量:125.4±26.6对108.5±23瓦,P = 0.03;无氧阈时的摄氧量:19.6±5.8对15.8±2.9毫升·分钟-1·千克-1;P = 0.02)。
这些结果表明,经皮经静脉二尖瓣交界切开术成功后,患者应进行运动以获得更好的功能改善。