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人类对快速省略刺激电位范式反应的动态特性。

Dynamic properties of the responses to fast omitted stimulus potential paradigm in human.

作者信息

Işoğlu-Alkaç U, Karamürsel S, Demiralp T, Devrim M

机构信息

Department of Physiology, Istanbul Faculty of Medicine, University of Istanbul, Turkey.

出版信息

Int J Neurosci. 1996 Dec;88(3-4):159-74. doi: 10.3109/00207459609000612.

DOI:10.3109/00207459609000612
PMID:9076563
Abstract

Visual evoked potentials (VEPs) and omitted stimulus potentials (OSPs) were analyzed on scalp recordings of 10 healthy subjects. OSP responses, obtained after the due-time of the first omitted stimulus at the end of a conditioning stimulus train have been studied mostly in animals. Two types of visual OSP responses were observed in the previous studies: slow (< or = 2 Hz) and fast (> or = 5 Hz). In this study, some dynamic properties of the responses to high frequency flash stimulation were investigated. Very short conditioning trains and even only two stimuli were found to be sufficient for the generation of an OSP response. With longer conditioning periods, of ca. 250 ms the OSP response develops and reaches its final size and shape, similar to the results obtained from animal studies. In the topographical analysis, the steady state response (SSR) amplitudes were found to be larger in the occipital and parietal regions while the OSP responses spread homogeneously in all subjects.

摘要

对10名健康受试者的头皮记录进行了视觉诱发电位(VEP)和遗漏刺激电位(OSP)分析。OSP反应是在条件刺激序列末尾第一个遗漏刺激的预定时间之后获得的,此前大多在动物身上进行研究。在先前的研究中观察到两种类型的视觉OSP反应:慢反应(≤2 Hz)和快反应(≥5 Hz)。在本研究中,对高频闪光刺激反应的一些动态特性进行了研究。发现非常短的条件刺激序列甚至仅两个刺激就足以产生OSP反应。随着约250毫秒的较长条件刺激期,OSP反应逐渐发展并达到其最终大小和形状,这与动物研究结果相似。在地形图分析中,发现枕叶和顶叶区域的稳态反应(SSR)幅度较大,而OSP反应在所有受试者中均匀分布。

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