Kintzer P P, Peterson M E
Boston Road Animal Hospital, Springfield, USA.
Vet Clin North Am Small Anim Pract. 1997 Mar;27(2):299-307. doi: 10.1016/s0195-5616(97)50033-7.
Cortisol-secreting adrenal tumors are responsible for 10% to 15% of all cases of naturally occurring canine hyperadrenocorticism. Differentiation of adrenal-dependent hyperadrenocorticism from pituitary-dependent hyperadrenocorticism is very important because the recommended therapeutic approaches for each are different, and the prognosis also may be different. A stepwise approach to diagnosing and staging the disease is needed. Treatment options include surgery and administration of mitotane or ketoconazole.
