Kobashi Y, Kawane H, Matsushima T, Okimoto N, Soejima R
Department of Medicine, Kawasaki Medical School.
Nihon Ronen Igakkai Zasshi. 1997 Jan;34(1):43-8. doi: 10.3143/geriatrics.34.43.
Between 1984 and September 1995, we prescribed home oxygen therapy for 155 patients (96 men and 59 women), mean age 68.6 years) with chronic respiratory failure. Here we describe the underlying diseases, laboratory findings (arterial blood gas analysis and pulmonary-function tests), and outcomes. We also report differences between those who were of least 70 years old (n = 82) and those less than 70 years old (n = 73). The underlying diseases were chronic obstructive pulmonary disease in 55 patients, lung cancer in 33, old pulmonary tuberculosis in 29, and pulmonary fibrosis in 27. Chronic obstructive pulmonary disease, especially pulmonary emphysema, was the most frequently encountered underlying disease in the older patients, whereas pulmonary fibrosis and lung cancer were most common in the younger patients. The duration of observation ranged from less than 1 month to 10 years. At the time of this study 82 patients had died, 31 were still being treated as outpatients at our hospital, 32 had transferred to other hospitals, and the status of 10 patients was unknown. The older and younger patients did not differ with regard to arterial blood gases, pulmonary function at the time home oxygen therapy began, or outcome: We believe that home oxygen therapy was very beneficial in these patients with chronic respiratory failure, because their quality of life improved after the start of this therapy.
1984年至1995年9月期间,我们为155例慢性呼吸衰竭患者(96例男性,59例女性,平均年龄68.6岁)开具了家庭氧疗处方。在此,我们描述其基础疾病、实验室检查结果(动脉血气分析和肺功能测试)及治疗结果。我们还报告了年龄在70岁及以上者(n = 82)与年龄小于70岁者(n = 73)之间的差异。基础疾病包括慢性阻塞性肺疾病55例、肺癌33例、陈旧性肺结核29例、肺纤维化27例。慢性阻塞性肺疾病,尤其是肺气肿,是老年患者中最常见的基础疾病,而肺纤维化和肺癌在年轻患者中最为常见。观察时间从不到1个月至10年不等。在本研究时,82例患者已死亡,31例仍在我院门诊接受治疗,32例已转至其他医院,10例患者情况不明。老年患者和年轻患者在动脉血气、开始家庭氧疗时的肺功能或治疗结果方面并无差异:我们认为家庭氧疗对这些慢性呼吸衰竭患者非常有益,因为在开始这种治疗后他们的生活质量得到了改善。