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糖尿病视网膜病变筛查项目作为预防失明的一项策略。

A diabetic retinopathy screening program as a strategy for blindness prevention.

作者信息

González Villalpando C, González Villalpando M E, Martínez Díaz S, Rivera Martínez D, Arredondo Pérez B, Islas Andrade S, Stern M P

机构信息

Centro de Estudios en Diabetes, American British Cowdray Hospital, Mexico D.F.

出版信息

Arch Med Res. 1997 Spring;28(1):129-35.

PMID:9078600
Abstract

The most frequent cause of preventable blindness in adults, in the developed world, is diabetic retinopathy (DR). The early treatable phase of this complication is clinically silent. In order to institute effective laser photocoagulation and prevention of blindness, timely detection is crucial. Consequently there is a need for periodic funduscopic examinations of all diabetics. Due to the high prevalence of DM in Mexico most of the primary care facilities are limited. We present the results of a DR screening program (DRSP) using a mobile unit equipped with a fundus photography camera, parked outside of a clinic. We report the prevalence of the various stages of DR and clinical characteristics observed in this population as well as our experience working in such an environment. The study period was from September 1 to December 22, 1995. All the diabetics that presented for care to the clinic were identified and all other persons were invited to participate. A total of 231 participants were invited (112 men, 119 women). Non-stereo fundus photos of two retinal fields (macula and optic disk centered) were taken with technique and classification according to international standards. Response rate to the invitation was 95.3%. Mean age was 62.4 +/- 13 years and 63.5 +/- 10 years and duration of diabetes was 12.3 +/- 10.1 years and 11.0 +/- 7.5 years for men and women, respectively. DR was detected in 38% of the cases, of these only 5.6% have received treatment. DR was uncovered in 84.5% of the cases and was associated with duration of diabetes (p < 0.001 in men and p = 0.04 in women) and hyperglycemia (in men p < 0.005, only). DR has a high prevalence in this population and can be detected through a screening program which reveals undiagnosed high risk DR in an efficient, and standardized manner.

摘要

在发达国家,成人可预防失明的最常见原因是糖尿病视网膜病变(DR)。这种并发症的早期可治疗阶段在临床上并无明显症状。为了进行有效的激光光凝治疗并预防失明,及时检测至关重要。因此,需要对所有糖尿病患者进行定期眼底检查。由于墨西哥糖尿病的高患病率,大多数初级保健机构资源有限。我们展示了一项糖尿病视网膜病变筛查项目(DRSP)的结果,该项目使用一辆配备眼底摄影相机的移动单元,停在一家诊所外。我们报告了该人群中观察到的DR各阶段患病率和临床特征,以及我们在这种环境下的工作经验。研究期间为1995年9月1日至12月22日。识别出所有到诊所就诊的糖尿病患者,并邀请所有其他人员参与。共邀请了231名参与者(112名男性,119名女性)。按照国际标准技术和分类方法,拍摄了两个视网膜区域(以黄斑和视盘为中心)的非立体眼底照片。邀请的响应率为95.3%。男性的平均年龄为62.4±13岁,糖尿病病程为12.3±10.1年;女性的平均年龄为63.5±10岁,糖尿病病程为11.0±7.5年。38%的病例检测出DR,其中仅5.6%接受过治疗。84.5%的病例发现了DR情况,且DR与糖尿病病程相关(男性p<0.001,女性p = 0.04)以及高血糖相关(仅男性p<0.005)。DR在该人群中患病率较高,可通过筛查项目以高效、标准化的方式检测出未被诊断的高风险DR。

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A diabetic retinopathy screening program as a strategy for blindness prevention.糖尿病视网膜病变筛查项目作为预防失明的一项策略。
Arch Med Res. 1997 Spring;28(1):129-35.
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