Conner J T, Bellville J W, Katz R L
Can Anaesth Soc J. 1977 Sep;24(5):559-64. doi: 10.1007/BF03005529.
Morphine 5 mg and 10 mg and meperidine 50 mg and 100 mg were studied as intravenous surgical premedicants in 160 patients. Relief of anxiety, sedation, lack of recall and side effects were the variables evaluated. Neither morphine nor meperidine proved to be particularly good surgical premedicants. There appeared to be no significant differences between the two drugs, but what differences there were tended to favor meperidine.
对160例患者进行了研究，将5毫克和10毫克吗啡以及50毫克和100毫克哌替啶作为静脉注射手术前用药。评估的变量包括焦虑缓解、镇静效果、无记忆以及副作用。结果表明，吗啡和哌替啶都不是特别理想的手术前用药。两种药物之间似乎没有显著差异，但存在的差异倾向于支持哌替啶。
