Haydar H S, He G W, Hovaguimian H, McIrvin D M, King D H, Starr A
Albert Starr Academic Center for Cardiac Surgery, Portland, Oregon, USA.
Eur J Cardiothorac Surg. 1997 Feb;11(2):258-65. doi: 10.1016/s1010-7940(96)01014-7.
Valve repair for aortic insufficiency may provide an alternative to aortic valve replacement in selected patients. This repair could be an attempt at permanent correction or palliation to allow the aortic annulus to grow and avoid the use of anticoagulation. Based upon a five-year experience, we proposed a classification according to valvular anatomy which could be a guide to patient and procedure selection.
Between September 1989 and February 1995, 44 consecutive patients underwent aortic valvuloplasty for aortic incompetence at our institution. Patients' ages ranged from 19 months to 76 years with a mean of 33 years. The etiology of aortic incompetence was congenital in 30 patients, degenerative in 7 patients, rheumatic in 5 patients, and infective endocarditis in 2. Aortic valve lesions were classified into three different types: type I, aortic annular dilation (8 patients); type II, excessive aortic leaflet tissue (12 patients); and type III, restricted leaflet motion with or without deficient leaflet tissue (24 patients). Type I needed commissural plication in 7 patients; and aortic annuloplasty, which was simple in 6 patients, and pericardial-augmented in 2. Type II necessitated midleaflet excision in 11 patients and leaflet plication in 7. Type III required leaflet extension in 19 patients, leaflet replacement in 1 patient, aortic valve commissurotomy in 13 patients augmentation commissurorrhaphy in 2, leaflet shaving in 4, and repair of leaflet perforation in 2.
Postoperative echocardiography revealed a significant decrease in the degree of aortic incompetence. Mean follow-up was 2.6 +/- 1.4 years. There was no mortality. Patients improved as is evident by NYHA functional class postoperatively. Eight of the first 13 patients (18%) needed reoperation. Three of these reoperations were bail-out procedures, and 3 patients (7%) who underwent the leaflet extension technique were reoperated upon 19 months to 3 years later. Presently, 23 patients are without anticoagulation, 11 take aspirin and 2 receive coumadin for combined mitral procedures.
Aortic valve repair provides a low risk option with satisfactory intermediate-term results for the treatment of aortic insufficiency in appropriately selected patients. Patient and procedure selection may be based upon the echocardiographic anatomy of the aortic valve, and a comparative risk benefit appraisal with valve replacement.
对于特定患者,主动脉瓣反流的瓣膜修复术可能是主动脉瓣置换术的一种替代方案。这种修复可以是尝试进行永久性矫正或姑息治疗,以使主动脉瓣环生长并避免使用抗凝药物。基于五年的经验,我们根据瓣膜解剖结构提出了一种分类方法,这可以作为患者和手术选择的指南。
1989年9月至1995年2月,我们机构连续44例患者因主动脉瓣关闭不全接受了主动脉瓣成形术。患者年龄从19个月至76岁不等,平均年龄为33岁。主动脉瓣关闭不全的病因中,先天性的有30例,退行性的有7例,风湿性的有5例,感染性心内膜炎的有2例。主动脉瓣病变分为三种不同类型:I型,主动脉瓣环扩张(8例);II型,主动脉瓣叶组织过多(12例);III型,瓣叶运动受限伴或不伴有瓣叶组织缺损(24例)。I型中,7例需要进行瓣叶交界折叠术;6例进行简单的主动脉瓣环成形术,2例进行心包增强主动脉瓣环成形术。II型中,11例需要进行瓣叶中叶切除,7例进行瓣叶折叠术。III型中,19例需要进行瓣叶延长术,1例进行瓣叶置换术,13例进行主动脉瓣交界切开术,2例进行交界缝合增强术,4例进行瓣叶削薄术,2例进行瓣叶穿孔修复术。
术后超声心动图显示主动脉瓣反流程度显著降低。平均随访时间为2.6±1.4年。无死亡病例。患者术后纽约心脏协会(NYHA)心功能分级改善明显。前13例患者中有8例(18%)需要再次手术。其中3例再次手术是补救性手术,3例(7%)接受瓣叶延长术的患者在19个月至3年后再次手术。目前,23例患者无需抗凝治疗,11例服用阿司匹林,2例因合并二尖瓣手术接受华法林治疗。
对于适当选择的患者,主动脉瓣修复术为治疗主动脉瓣反流提供了一种低风险选择,中期结果令人满意。患者和手术选择可基于主动脉瓣的超声心动图解剖结构以及与瓣膜置换术的风险效益比较评估。