Chard T
Department of Reproductive Physiology, St Bartholomew's Hospital Medical College, London, UK.
Hum Reprod Update. 1995 Jul;1(4):385-96. doi: 10.1093/humupd/1.4.385.
The process of implantation in the human involves 'invasion' of the maternal endometrium by the trophoblast surrounding the developing blastocyst, in response to which there is a cellular reaction in the endometrium. The overall situation has some features analogous to invasion by a tumour and some which are more characteristic of an inflammatory response. In addition, and also in common with cancer and inflammation, there is a release of biologically active molecules, including cytokines, at and around the implantation site. It is believed that these cytokines may play an important role in the successful establishment of the pregnancy; the evidence for this belief is examined in this review.
人类的着床过程涉及围绕发育中的囊胚的滋养层对母体子宫内膜的“侵入”，作为对此的反应，子宫内膜会发生细胞反应。总体情况有一些类似于肿瘤侵袭的特征，也有一些更具炎症反应的特征。此外，与癌症和炎症一样，在着床部位及其周围会释放包括细胞因子在内的生物活性分子。人们认为这些细胞因子可能在成功建立妊娠中起重要作用；本综述将审视这一观点的证据。
