Bezlepkin V G, Sirota N P, Gaziev A I
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
Mech Ageing Dev. 1996 Dec 20;92(2-3):227-34. doi: 10.1016/s0047-6374(96)01840-4.
The effect of daily dietary supplements of an antioxidant mixture (AM) consisting of beta carotene, alpha tocopherol, ascorbic acid, rutin, selenium, and zinc on the survival of male C57BL/6 mice starting at 2, 9, 16, and 23 months of age was investigated. The survival of mice given AM starting at 2 and 9 months of age was found to increase significantly (from 86 to 108 days) compared to the control. The times, of 50, 90, and 100% mortality in mice given AM starting at 2 and 9 months of age increased by 16-9.5% compared to the control, whereas in mice given AM, starting at 16 and 23 months of age, no effect was observed.
研究了从2、9、16和23月龄开始每日膳食补充由β-胡萝卜素、α-生育酚、抗坏血酸、芦丁、硒和锌组成的抗氧化剂混合物（AM）对雄性C57BL/6小鼠存活的影响。发现从2和9月龄开始给予AM的小鼠的存活率与对照组相比显著提高（从86天提高到108天）。从2和9月龄开始给予AM的小鼠中50%、90%和100%死亡率的时间比对照组增加了16 - 9.5%，而从16和23月龄开始给予AM的小鼠未观察到效果。
