Rosso L, Zuber E, Pichat C, Flandrois J P
Pôle de Compétence en Sécurité des aliments (food Safety Centre of Expertise) Crealis, Danone, Z.I. du Teinchurier, Brive, France.
Int J Food Microbiol. 1997 Mar 18;35(1):75-81. doi: 10.1016/s0168-1605(96)01231-7.
A simple relationship was observed in growth medium, between the dissociation constant (via the pKa) of the acid used to control pH and the minimum pH at which Salmonellae and Escherichia coli initiate growth. From this new relationship, a simple method was proposed to predict the minimum growth pH for a given strain and different acid types. This method, illustrated on Listeria monocytogenes, would merely require the knowledge of two minimum pH values, one for a strong acid (e.g. hydrochloric acid) and one for a weak acid (e.g. acetic or propionic acid). From these two values, it seems possible to estimate for a given growth medium, the minimum pH value for any other acid within the defined pKa range.
在生长培养基中，观察到用于控制pH值的酸的解离常数（通过pKa）与沙门氏菌和大肠杆菌开始生长的最低pH值之间存在简单的关系。基于这种新关系，提出了一种简单的方法来预测给定菌株和不同酸类型的最低生长pH值。以单核细胞增生李斯特菌为例，该方法仅需要知道两个最低pH值，一个是强酸（如盐酸）的，另一个是弱酸（如乙酸或丙酸）的。根据这两个值，似乎可以估计给定生长培养基中定义的pKa范围内任何其他酸的最低pH值。
