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成人胆总管囊肿的外科治疗:结果与长期随访

Surgical treatment of choledochal cyst in adults: results and long-term follow-up.

作者信息

Chen H M, Jan Y Y, Chen M F, Wang C S, Jeng L B, Hwang T L, Chen S C, Chao T C

机构信息

Deparment of Surgery, Change Gung Memorial Hospital, Taipei, Taiwan.

出版信息

Hepatogastroenterology. 1996 Nov-Dec;43(12):1492-9.

PMID:9081911
Abstract

BACKGROUND/AIMS: Results of the surgical management of 60 adults with choledochal cysts at Chang Gung Memorial Hospital Taipei are presented.

PATIENTS AND METHODS

All patients were diagnosed and surgically managed during the period between March 1979 and December 1992. There were 47 females and 13 males, with ages ranging from 16 to 81 years (mean age = 31.9 years). Of the total, there were 41 Type I, one Type II, 14 Type IV, and four Type V choledochal cysts classified according to Todani's classification system. The definite surgical procedures were cyst excision and hepatico-jejunostomy in 43 cases in type I and IV diseases, one cyst excision in type II disease, two hepatectomy for type V disease, cyst enterostomy in seven cases, and T-tube choledochocystostomy in seven cases.

RESULTS

The operative mortality rate was 3.3% and the complication rate related to the surgical procedure was 20%. Early postoperative complications include wound infection, leakage of anastomosis, acute pancreatitis, septic shock, left pleural effusion, and intra-abdominal abscessing. Reoperations were needed in the early postoperative days in two cases due to hepatico-jejunostomy leakage and intraabdominal abscess formation. Long-term surgical outcome, concerning recurrence of symptoms, was related to the following factors, excluding the factors of surgery: presence of bile duct lithiasis, common channel less than 22 mm, presence of preoperative pancreatitis and acute angle type pancreaticobiliary unions. Only common channel less than 22 mm is statistically significant. The percentage of recurrence of the symptoms after resectional surgery was 32.5% in the long term follow-up period. Most of the cases responded well to an antibiotics treatment. Three of the cases required a second operation or PTCD as well as dilatation to treat the recurrent cholangitis.

CONCLUSION

Although the recurrence of symptoms is not uncommon and satisfactory explanation of the analysed factors is still the treatment of choice for adult patients with choledochal cysts.

摘要

背景/目的:本文介绍了台北长庚纪念医院对60例胆总管囊肿成年患者的手术治疗结果。

患者与方法

所有患者均于1979年3月至1992年12月期间确诊并接受手术治疗。其中女性47例,男性13例,年龄范围为16至81岁(平均年龄=31.9岁)。根据Todani分类系统,总共有41例I型、1例II型、14例IV型和4例V型胆总管囊肿。I型和IV型疾病的43例患者明确的手术方式为囊肿切除和肝管空肠吻合术,II型疾病1例行囊肿切除术,V型疾病2例行肝切除术,7例行囊肿造口术,7例行T管胆总管囊肿造瘘术。

结果

手术死亡率为3.3%,与手术相关的并发症发生率为20%。术后早期并发症包括伤口感染、吻合口漏、急性胰腺炎、感染性休克、左侧胸腔积液和腹腔内脓肿形成。2例患者术后早期因肝管空肠吻合口漏和腹腔内脓肿形成需要再次手术。长期手术结果,就症状复发而言,与以下因素有关,不包括手术因素:胆管结石的存在、共同通道小于22mm、术前胰腺炎的存在以及胰胆管汇合部锐角型。只有共同通道小于22mm具有统计学意义。在长期随访期内,切除术后症状复发的百分比为32.5%。大多数病例对抗生素治疗反应良好。3例患者需要二次手术或经皮肝穿刺胆管引流(PTCD)以及扩张治疗复发性胆管炎。

结论

尽管症状复发并不罕见,且对分析因素的满意解释仍是成年胆总管囊肿患者的首选治疗方法。

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