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[听神经瘤中用耳声发射畸变产物评估耳蜗功能]

[Assessment of cochlear function with distortion products of otoacoustic emissions in acoustic neuroma].

作者信息

Oeken J

机构信息

Universitäts-HNO-Klinik Leipzig.

出版信息

HNO. 1996 Dec;44(12):677-84.

PMID:9081952
Abstract

Unilateral hearing loss (HL) caused by an acoustic neuroma (AN) is regarded to be neural ("non-cochlear"). By using otoacoustic emissions it is possible to prove concurrent sensory (cochlear) HL. We prefer distortion-product otoacoustic emissions (DPOAE) because these are more frequency-specific and stable. From April 1994 to May 1996, we examined preoperatively 24 patients with radiologically proven AN. Pure-tone audiometry, DP-grams, brainstem-evoked response audiometry (BERA) and vestibular studies were performed in all cases, while special auditory tests (Fowler, Carhart) and short increment sensitivity indices were also performed in 12 cases. BERA was pathological in 23 cases and latencies were borderline in one case. After comparing audiograms and DP-grams we found 13 patients with sensory HL, 4 patients with combined sensorineural HL and 7 patients with neural HL. There was a strong correlation between the results of DPOAE and the results of special auditory test (phi = 0.63) whereas there was no correlation between tumor size and cochlear function. The result showed that the typical HL caused by AN was a combined sensorineural loss. DPOAE were not suited for the detection of AN but were able to give exact information about any remaining cochlear function.

摘要

由听神经瘤(AN)引起的单侧听力损失(HL)被认为是神经性的(“非耳蜗性”)。通过使用耳声发射可以证实同时存在感觉性(耳蜗性)HL。我们更倾向于使用畸变产物耳声发射(DPOAE),因为它们在频率方面更具特异性且更稳定。1994年4月至1996年5月,我们对24例经放射学证实患有AN的患者进行了术前检查。所有病例均进行了纯音听力测定、DP图、脑干诱发电位听力测定(BERA)和前庭研究,同时12例患者还进行了特殊听觉测试(福勒、卡哈特)和短增量敏感指数测试。23例患者的BERA结果异常,1例患者的潜伏期处于临界状态。在比较听力图和DP图后,我们发现13例患者存在感觉性HL,4例患者存在混合性感觉神经性HL,7例患者存在神经性HL。DPOAE结果与特殊听觉测试结果之间存在很强的相关性(phi = 0.63),而肿瘤大小与耳蜗功能之间没有相关性。结果表明,AN引起的典型HL是混合性感觉神经性听力损失。DPOAE不适合用于检测AN,但能够提供有关任何剩余耳蜗功能的确切信息。

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