MMWR Morb Mortal Wkly Rep. 1997 Mar 14;46(10):221-4.
Aseptic meningitis (AM) is a severe, nonbacterial infection of the central nervous system that affects an estimated 30,000-50,000 persons each year in the United States. On July 21, 1995, the infection-control coordinator of the county hospital in Whiteside County (1990 population: 60,000), Illinois, reported to CDC an outbreak of AM. From June 7 through July 21, 1995, a total of 29 persons had onset of clinical AM, characterized by fever, headache, stiff neck, and photophobia. Many cases had cerebrospinal fluid (CSF) pleocytosis, and all had negative bacterial cultures. Preliminary identification of an enterovirus was made from virus-isolation studies. This report describes the investigation of this outbreak by county and state health officials, which indicated that, although members of the community were concerned about possible transmission at large public gatherings and several swimming locations, there was no risk for illness in these settings.
无菌性脑膜炎(AM)是一种严重的中枢神经系统非细菌性感染,在美国每年估计影响30000至50000人。1995年7月21日,伊利诺伊州怀特塞德县(1990年人口:60000)县医院的感染控制协调员向疾病控制与预防中心报告了一起AM疫情。1995年6月7日至7月21日,共有29人出现临床AM症状,其特征为发热、头痛、颈部僵硬和畏光。许多病例出现脑脊液(CSF)细胞增多,且所有病例的细菌培养均为阴性。通过病毒分离研究初步鉴定为肠道病毒。本报告描述了县和州卫生官员对此次疫情的调查,结果表明,尽管社区成员担心在大型公共集会和几个游泳场所可能发生传播,但在这些场所不存在患病风险。