[僵人综合征中的节律性循环调节障碍]

[Rhythmic circulatory dysregulation in stiff man syndrome].

作者信息

Diedrich U

机构信息

Neurologische Universitätsklinik, Göttingen.

出版信息

Nervenarzt. 1996 Dec;67(12):1027-9. doi: 10.1007/s001150050087.

DOI:10.1007/s001150050087

PMID:9082192

Abstract

A woman with severe stiff-man syndrome showed periodic cardiovascular dysregulation. The blood pressure changed spontaneously every 5-10 min. This rhythm was also maintained after relaxation. However, the vegetative and motoric disturbances disappeared after intrathecal application of baclofen. It is speculated that spinal GABAergic mechanisms are responsible for the tonic regulation of the cardiovascular system.

摘要

一名患有严重僵人综合征的女性出现周期性心血管调节异常。血压每5 - 10分钟自发变化一次。这种节律在放松后也能维持。然而，鞘内注射巴氯芬后自主神经和运动障碍消失。据推测，脊髓γ-氨基丁酸能机制负责心血管系统的紧张性调节。