Higuchi Y, Maihara T, Hattori H, Furusho K, Okazawa H, Ishizu K, Yonekura Y
Department of Paediatrics, Faculty of Medicine, Kyoto University, Japan.
Eur J Pediatr. 1997 Mar;156(3):236-8. doi: 10.1007/s004310050591.
Two preterm infants with extensive periventricular leukomalacia (PVL) were examined by [18F]-fluorodeoxyglucose-positron emission tomography (FDG-PET) at the corrected ages of 18 and 34 days. They showed similar clinical courses including oculoclonic seizure, hypsarrhythmia and severe mental retardation, in addition, to spastic quadriplegia. FDG-PET study of these two infants with severe PVL disclosed poorly developed metabolic activity in the primary sensorimotor cortex, while the MRI images displayed only periventricular white matter lesions.
Positron emission tomography may disclose cortical involvement in infants with severe periventricular leukomalacia.
两名患有广泛脑室周围白质软化症（PVL）的早产儿在矫正年龄18天和34天时接受了[18F] -氟脱氧葡萄糖正电子发射断层扫描（FDG-PET）检查。他们表现出相似的临床病程，包括眼球阵挛性癫痫、高度节律失调以及严重智力障碍，此外还有痉挛性四肢瘫痪。对这两名患有严重PVL的婴儿进行的FDG-PET研究显示，初级感觉运动皮层的代谢活动发育不良，而MRI图像仅显示脑室周围白质病变。
正电子发射断层扫描可能揭示严重脑室周围白质软化症婴儿的皮质受累情况。
